产品货号:
LA10413
中文名称:
二氢细胞松弛素B
英文名称:
Dihydrocytochalasin B
产品规格:
1mg
发货周期:
1~3天
产品价格:
询价
CAS号 | 39156-67-7 |
分子式 | C29H39NO5 |
分子量 | 481.62 |
外观 | 白色结晶 |
熔点 | 203~205℃ |
溶解性 | 溶于有机溶剂如乙醇(20mg/ml)DMSO(20mg/ml) |
炽灼残留 | <0.1% |
纯度 | >98% |
重金属 | <0.002% |
储存条件 | -20℃ |
用途及描述 | 科研试剂,用于膜蛋白的溶解,透化细胞和细胞核膜 |
生物活性
Dihydrocytochalasin B (DCB) is a member of the cytochalasin mycotoxin family that inhibits actin assembly.It blocks cleavage furrow formation and cytokinesis in synchronous HeLa cells at a concentration of 10μM.DCB induces tetraploidy and arrests the cell cycle indefinitely in the G1 phase in REF-52 cells.It also increases the drug sensitivity of multidrug resistant SKVLB1 cells to paclitaxel and doxorubicin in vitro.
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